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Stem Cells 8: Regulation of the HSC Niche by Mesenchymal Stem/stromal Cells (MSC)
stem cells

Stem Cells 8: Regulation of the HSC Niche by Mesenchymal Stem/stromal Cells (MSC)

HSC niche refers to a highly specialized and unique microenvironment that provides hematopoietic stem cells (HSCs) with…

Stem Cells 7: Hematopoietic Stem Cells (HSC)
stem cells

Stem Cells 7: Hematopoietic Stem Cells (HSC)

We have examined mesenchymal stem/stromal cells (MSCs) in detail in the previous articles. Now, let us turn our attenti…

Stem Cells 6: Therapeutic Approaches Based on Mesenchymal Stem/Stromal Cells (MSC)
stem cells

Stem Cells 6: Therapeutic Approaches Based on Mesenchymal Stem/Stromal Cells (MSC)

In this article, we will explore various therapeutic approaches utilizing mesenchymal stem cells (MSCs). MSC-Based Ther…

Stem Cells 5: MSC-Based Therapies and Clinical Trials for Autoimmune and Other Diseases
stem cells

Stem Cells 5: MSC-Based Therapies and Clinical Trials for Autoimmune and Other Diseases

MSCs Showing Both Aspects of Stromal Cell and Stem Cell In the previous articles, we examined how MSCs suppress inflamm…

Stem Cells 4: Immunomodulatory Actions of Mesenchymal Stem/stromal Cells — Paracrine Mechanisms
stem cells

Stem Cells 4: Immunomodulatory Actions of Mesenchymal Stem/stromal Cells — Paracrine Mechanisms

Immunoregulation of MSC: Creation of an Anti-inflammatory Environment Let’s take a closer look at how MSCs contribute t…

Stem Cells 3: Research History and Phenotypes(Anti or Pro-inflammatory) of Mesenchymal Stem/Stromal Cells
stem cells

Stem Cells 3: Research History and Phenotypes(Anti or Pro-inflammatory) of Mesenchymal Stem/Stromal Cells

Introduction to the Concept of Stroma The actual multipotent differentiation ability of mesenchymal stem cells remains …

Stem Cells 2: Mesenchymal Stem Cells (MSC) and Epithelial–Mesenchymal Transition (EMT)
stem cells

Stem Cells 2: Mesenchymal Stem Cells (MSC) and Epithelial–Mesenchymal Transition (EMT)

Stages of Stem Cell Differentiation Potential (Totipotent → Pluripotent → Multipotent) Let’s summarize the stages of st…

stem cells 1: Embryonic Development Process (Including Subdivision of the Mesoderm)
stem cells

stem cells 1: Embryonic Development Process (Including Subdivision of the Mesoderm)

Through a series of writings about bones, we have seen that most bones are covered on the outside by dense cortical bon…

Bone 10: Osteoporosis Treatments – Anabolic Agents
Basic Biology

Bone 10: Osteoporosis Treatments – Anabolic Agents

Bone Formation Promoting Agents (Anabolics) 1. Parathyroid Hormone (PTH) Analogs Fundamentally, parathyroid hormone (PT…

Bone 9: Osteoporosis Treatments – Antiresorptive Agents
Basic Biology

Bone 9: Osteoporosis Treatments – Antiresorptive Agents

Osteoporosis Bone homeostasis is maintained through a balanced, continuous cycle of cooperation between osteoclasts, wh…

Bone 8: Vitamin K, Gamma-Carboxylation and osteocalcin
Basic Biology

Bone 8: Vitamin K, Gamma-Carboxylation and osteocalcin

Gamma-Carboxylation (γ-carboxylation)   Bone formation and vitamin K are closely connected biochemically. To understand…

Bone 7: Function and biosynthesis of Vitamin D
Basic Biology

Bone 7: Function and biosynthesis of Vitamin D

Vitamin D and Bone Formation Let us now further explore the key factors involved in bone formation—Vitamin D and Vitami…

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